abstract：OBJECTIVE:To improve the prognosis and therapeutic efficacy of Waldeyer's ring non-Hodgkin lymphoma (NHL-WR), combined radio-chemotherapy was used to treat the patients with NHL-WR and prognostic factors were analyzed. METHODS:Ninety patients with stage I-IV NHL-WR were treated with combined radio-chemotherapy. 4000 c...

journal_title：Chinese medical journal

authors： Yong W,Zhang Y,Zheng W,Wei Y

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:To investigate the occurrence and extent of apoptosis in the course of restenosis. METHODS:The experimental models of vessel narrowness and intima thickness were established in minipigs' iliac arteries by balloon injury and specimens were retrieved on the 1st, 3rd, 6th, 12th and 30th days for dynamic observa...

journal_title：Chinese medical journal

authors： Huang J,Yin H,Leng J,Yao Y,Yao R,Peng T,Li J

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of Q-switched alexandrite laser irradiation on dermal melanocytes of nevus of Ota. METHODS:Multiple biopsies were carried out on 4 patients with nevus of Ota before and after laser irradiation. Altogether 11 samples were examined under light microscope and 14 under transmission elec...

journal_title：Chinese medical journal

authors： Lu Z,Chen J,Wang X,Fang L,Jiao S,Huang W

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To investigate the expressions of hypothalamic arginine vasopressin (AVP) mRNA, renal AVP V2 receptor mRNA, and AVP-dependent aquaporin-2 (AQP2) mRNA in rats with adriamycin-induced nephrotic syndrome. Effects of Chinese herb Astragalus membranaceus (AM) were also tested. METHODS:Sprague-Dawley rats with fou...

journal_title：Chinese medical journal

authors： Ma J,Fan S,Chen J,Gu Y,Lin S

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To induce islet grafting tolerance by intravenous injection of anti-CD4, anti-CD8 immunotoxins and donor soluble antigen. METHODS:Fourteen days or 7 days prior to transplantation, the immunotoxin of anti-CD4, anti-CD8 200 micrograms respectively, and donor soluble antigen 500 micrograms were intravenously in...

journal_title：Chinese medical journal

authors： Lan P,Yan L,Xiao L

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To study the experience in the treatment of subclavian steal syndrome (SSS) and the relation between SSS and the damage of brain. METHODS:In 28 patients with SSS, 23 were operated on. They complained of vertigo, TIA, and claudication of arms. One patient suffered from severe stem ischemia spasm. All the pati...

journal_title：Chinese medical journal

authors： Guan H,Liu C,Yu Z

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To review the relationship between personal behavior and cultural factors and reproductive tract infections (RTIs). METHODS:An English-language literature search using MEDLINE (1994-1998), Social Science Index (1994-1998), and informal discovery. Any original researches and reviews related to RTIs' epidemiol...

journal_title：Chinese medical journal

authors： Guo S

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To explore the relationship between interleukin-8 (IL-8) and airway hyper-responsiveness (AHR) of asthma in guinea pigs. METHODS:IL-8 at a dose of 0.5 microgram/kg or 5.0 micrograms/kg was administered intranasally to guinea pigs twice a week for 3 weeks. 24 hours after the last administration, airway respon...

journal_title：Chinese medical journal

authors： Qi H,Lu K,Wang W

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To summarize the progress of surgical treatment of hepatocellular carcinoma (HCC) and related basic research at the Liver Cancer Institute of Shanghai Medical University in the recent years, with special reference to recurrence and metastasis. METHODS:Published and unpublished update clinical and experimenta...

journal_title：Chinese medical journal

authors： Tang Z,Zhou X,Lin Z,Yang B,Ma Z,Ye S,Wu Z,Fan J,Liu Y,Liu K,Qin L,Tian J,Sun H,He B,Xia J,Qiu S,Zhou J

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:To explore the mechanism of autoimmune hemolysis and establish a more sensitive test for autoimmune hemolytic anemia (AIHA). METHODS:IgG subclasses were tested in 40 patients with idiopathic or secondary AIHA by Coombs test with monoclonal antibodies. Hb, TBil, RC and FHb, as hemolytic parameters, were used ...

journal_title：Chinese medical journal

authors： Li Z,Shao Z,Xu Y,Shen L,Chen G,Zhang Y,Chu Y

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:To study the interaction between oncogene mdm2 and wp53 in human glandular lung cancer cell line GLC-82. METHODS:By lipofectamine-mediated DNA transfection, wp53 and mdm2 were transfected separately or co-transfected into GLC-82 cells via retrovival vector pDOR-neo, a carrier of wp53 and mdm2. RESULTS:The g...

journal_title：Chinese medical journal

authors： Li P,Rao G,Chen Y,Ding Z,Yu W

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:To study protective immunity afforded by murine immunization with DNA vaccine of Schistosoma japonicum (S. japonicum) as measured by reduction in worm burden and host antibody, cytokines. METHODS:DNA vaccine pCD-Sj32 was constructed, identified and expressed. pCD-Sj32 could induce substantial protective immu...

journal_title：Chinese medical journal

authors： Shi Y,Xie L,Li C,Han J

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of Burn Healing Liquid (BHL) on the proliferation of keratinocytes and fibroblasts and to explore the potential effect of BHL on fibroblast contraction. METHODS:Human keratinocytes and dermal fibroblasts were cultured in media containing serial dilutions of BHL followed by cell pro...

journal_title：Chinese medical journal

authors： Su Y,Chen B,Thang PT,Hughes MA,Xu X,Cherry GW

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:To study the expression of vascular endothelial growth factor (VEGF) in different parts of heart during early acute myocardial ischemia. METHODS:The expression of VEGF in control and study group in rats was performed with the Strept Avidin-Biotin-Peroxidase Complex (SABC) method. RESULTS:A rapid expression ...

journal_title：Chinese medical journal

authors： Chen J,Xu X,Wu X,Zhu J

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:To determine the relationship between remodeling and dysfunction of left ventricle (LV) and the expression of the angiotensin II AT1 receptor mRNA after myocardial infarction (MI) in rats. METHODS:Nine MI rats (Group A) and 8 sham-operated rats (Group B) were studied by both Doppler echocardiography and Dot ...

journal_title：Chinese medical journal

authors： Zhang G,Yang Y,Pu S,Shen X,Peng T,Chen H

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To understand the relationship among congenital choledochal cyst, anomalous junction of pancreaticobiliary duct (AJPBD) and pancreatitis. METHODS:25 children with choledochal cyst treated in our hospital were included in this study. Their ages ranged from 2 months to 14 years. Intraoperative cholangiography ...

journal_title：Chinese medical journal

authors： Zhao L,Li Z,Ma H,Zhang X,Mou X,Zhang D,Lin W,Niu A

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of nitric oxide inhibitor on prostacyclin (PGI2) biosynthesis and the role of PGI2 in hyperhemodynamics of portal hypertension. METHODS:Sprague Dawley rats were divided into four groups: intrahepatic portal hypertension (IHPH) by injection of CCl4, prehepatic portal hypertension (PHPH...

journal_title：Chinese medical journal

authors： Cao H,Wu Z,Zhou J,Chen Z,Kuang Y

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:To explore the relationship between apoptosis and spontaneous hypertension, and the effect of angiotensin converting enzyme (ACE) inhibitor on apoptosis. METHODS:Male spontaneously hypertensive rats (SHR) and normotensive control rats (WKY) at different ages were used, meanwhile, the treatment of SHR with ra...

journal_title：Chinese medical journal

authors： Peng L,Bradley CJ,Zulli A,Liu JJ

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:To determine whether extraadrenal tissues synthesize aldosterone in addition to vascular tissue and brain. METHODS:Ex vivo kidney perfusion was performed in normal Wistar rats, ACEI pretreated and adrenalectomized rats prior to the perfusion experiment. After equilibration for 30 minutes, 120 ml of perfusate...

journal_title：Chinese medical journal

authors： Wu P,Liang X,Dai Y,Liu H,Zang Y,Guo Z,Zhang R,Lai W,Zhang Y,Liu Y

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:To study 4 cases of adult T-cell leukemia/lymphoma (ATLL) associated with cutaneous lesions for clinicopathology, immunophenotype, human T-cell leukemia/lymphoma virus type I (HTLV-I) provirus DNA and their ultrastructure. At the same time, HTLV-I provirus DNA of ATLL patients were also compared with 18 cases...

journal_title：Chinese medical journal

authors： Wang C,Yao Z,Liao J,Luo Y,Ma Y,Chen G,Zhu W

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:To investigate whether PreS1 antigen and/or anti-PreS1 antibody in serum might have some significance different from routine hepatitis B virus (HBV) markers in hepatitis B virus infection. METHODS:Forty-six acute hepatitis B patients and 377 chronic persistent hepatitis patients were examined to assess the c...

journal_title：Chinese medical journal

authors： Mi Z,Feng F,Zhang X,Lian Z,Wang H,Tong Y

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVES:To study the interrelation between nitric oxide (NO) and endothelin-1 (ET1) in experimental acute hypoxic rats, and to evaluate the mechanism of acute hypoxic pulmonary hypertension affected by NO and ET1 and its intervention. METHODS:Nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase histochemi...

journal_title：Chinese medical journal

authors： Wang Y,Zhang L,Shen W,Chen L,Fan S

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:To explore the methods of lens-sparing (without lensectomy), non-silicone oil tamponade and no scleral buckling for treatment of early giant retinal tears. METHODS:Thirteen cases of early retinal detachment of proliferative vitreoretinopathy (PVR) grade C2-D1, with giant tear extending from 135 degrees to 27...

journal_title：Chinese medical journal

authors： Xu X,Zhang X,Wu N,Ho PC

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To explore the possibility of using specific antigens for immunodiagnosis of hookworm disease in endemic area. METHOD:Infective third-stage larvae of the canine hookworm, Ancylostoma caninum (A. caninum), were prepared as the source of antigen. Enzyme-linked immunoelectrotransfer blotting (EITB) was employed...

journal_title：Chinese medical journal

authors： Xue H,Liu S,Ren H,Qiang H,Xiao S,Feng Z,Hotez P

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To determine the effects and toxicity of interstitial brachytherapy using iridium-192 on brain malignant gliomas. METHODS:Between January 1992 and January 1995, 56 patients with anaplastic astrocytoma and glioblastoma multiforme were treated with stereotactic brachytherapy using temporary high-activity iridi...

journal_title：Chinese medical journal

authors： Liu Z,Yu X,Guo Y,Li S,Cui Y,Yu X,Yuan Z,Kang J

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:To study if the functions of C gene and its promotor are related to the pathogenesis of hepatitis B and to describe their hot spot mutations in Chinese patients. DATA SOURCES:We have studied this subject in recent years. A mini-review is based on some unpublished works. DATA SELECTION:The sequence data of C...

journal_title：Chinese medical journal

authors： Luo K

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVES:To get a more comprehensive recognition about carpal tunnel syndrome (CTS), especially the manual housework as its risk factor, and to facilitate early diagnosis and proper treatment. METHODS:262 CTS patients (396 CTS hands) were analyzed retrospectively. A 1:1 matched case-control study of 61 woman pairs i...

journal_title：Chinese medical journal

authors： Tang X,Zhuang L,Lu Z

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:To study the effect of pericardial devascularization combined with Latarjet's innervation on portal hypertension. METHODS:Forty-eight patients undergoing pericardial devascularization combined with Latarjet's innervation were compared with 57 patients with devascularization. Clinical results were evaluated b...

journal_title：Chinese medical journal

authors： Li S,Wu E,Huang J,Luo C

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVE:To explore the involvement of calcium in the mechanism of hypoxic/hypoglycemic insults and nerve growth factor (NGF) protection. METHODS:Neuron viability and lactate dehydrogenase (LDH) efflux in the bathing medium in cerebral cortex cultures from fetal rats were measured. Calcium fluorescent indicator Fura-...

journal_title：Chinese medical journal

authors： Wu J,Zhang J

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:To describe the clinical features, operative methods and postoperative management of the intra-axial tumors of medullocervical junction, and to make differential diagnosis for different subtypes. METHODS:Fifteen patients with intra-axial tumors of medullocervical junction were treated from August 1988 to Jun...

journal_title：Chinese medical journal

authors： Xu Q,Bao W,Mao R,Pang L

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:To investigate the feasibility of adrenal sparing surgery for selected renal cell carcinoma (RCC), since the necessity of routine adrenalectomy during radical nephrectomy for RCC has been challenged in recent years. METHODS:178 patients underwent perifascial nephrectomy in a 16-year period. Of these patients...

journal_title：Chinese medical journal

authors： Xu C,Niu Z,Lü J,Wang J

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:To study the effect for albendazole therapy for alveolar echinococcus infection in gerbils and mice. METHODS:Mice and gerbils were infected of metacestode tissues by intraperitoneal (i.p.) transplantation and treated with albendazole-medicated feeds. The effects were evaluated by comparison of the treated an...

journal_title：Chinese medical journal

authors： Liu Y,Wang X,Gao J,Yao Y,Yu D

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:To investigate the incidence rate, pathologic changes, mechanisms and diagnostic methods in renal bone disease. METHODS:The blood levels of carboxyterminal parpthyriod hormone (C-PTH), 1,25(OH)2D3, calcium and phosphate, aluminum in serum and bone tissue were measured. The bone biopsy and bone scan with 99m ...

journal_title：Chinese medical journal

authors： Zhu P,Wang G,Yu Y,Lou D,Wang S,Jia J,Dong D

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of gynostemma pentaphyllum mak (GP) on carcinomatous conversions of leukoplasia of the golden hamster cheek pouch induced by dimethylbenzanthracene (DMBA). METHODS:284 golden hamsters, ranging from 4 to 8 weeks of age, 80 to 100 grams in weight were randomly divided into three groups: ...

journal_title：Chinese medical journal

authors： Zhou Z,Wang Y,Zhou Y,Zhang S

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:To evaluate whether hypermethylation of calcitonin (CT) gene could serve as a transforming signal of myelodysplastic syndrome (MDS) to leukemia. METHODS:Bone marrow aspirates from 35 MDS patients, including 25 refractory anemia (RA), 10 refractory anemia with excess of blasts (RAEB) or refractory anemia with...

journal_title：Chinese medical journal

authors： Wu S,Xie G,Bai R,Wang Y,Zhu P

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To study the effect of the body proportion and pubertal growth spurt on the stature of children with beta-thalassaemia major. METHODS:The height, sitting height, upper to lower segment (U:L) ratio and pubertal development were determined in 71 Chinese children (38 girls and 33 boys) with beta-thalassaemia. T...

journal_title：Chinese medical journal

authors： Low CK,Kwan YW,Cheung PT,Li MC,Ha SY,Lau YL,Karlberg J

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To observe the anti-injury role of recombinant human augmenter of liver regeneration. METHODS:To establish liver injury models induced by CCl4 in vivo and in vitro, cell survival rates and LDH release rates served as observing index in experiments in vitro. Survival rates of liver failure animals, serum conc...

journal_title：Chinese medical journal

authors： Yang X,Wang A,Zhou P,Wang Q,Wei H,Wu Z,He F

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that in a rat model of acute intestinal ischemia/reperfusion injury, endotoxemia from the gastrointestinal tract would play a role in mediating tumor necrosis factor (TNF) response and remote organ dysfunction. METHODS:Wistar rats underwent 45 minutes of superior mesenteric artery occl...

journal_title：Chinese medical journal

authors： Yao Y,Yu Y,Wu Y,Shi Z,Sheng Z

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:Familial hypertrophic cardiomyopathy (FHCM) is a primary myocardial disease characterized by unexplained ventricular hypertrophy. The application of the techniques of reverse genetics has identified at least five chromosomal loci as the major causes for FHCM in diverse ethnic populations, suggesting substanti...

journal_title：Chinese medical journal

authors： Ko YL,Teng MS,Tang TK,Chen JJ,Lee YS,Wu CW,Lien WP,Liew CC

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:To develop a diagnostic framework that would help defining clinical problems by the expanded understanding with traditional Chinese medicine (C Med) and western medicine (W Med). METHODS:The basic attributes of diagnosis and the use of diagnostic techniques of W Med and C Med are reviewed. Some of the variou...

journal_title：Chinese medical journal

authors： Yu EC

更新日期：1998-05-01 00:00:00